Now a part of Advanced Dermatology and Cosmetic Surgery
QWO - Maragh Dermatology, Surgery & Vein Institute


What is QWO®?

QWO is the first and only FDA-approved injectable for the treatment of moderate to severe cellulite in the buttocks of adult women.

How does QWO work?

Enzymes called collagenases target the structural causes under the skin, where cellulite starts. It’s thought that QWO works by releasing fibrous bands, redistributing fat cells, and stimulating the growth of new collagen. How QWO works in moderate to severe cellulite is not fully understood.

Is QWO a surgical procedure?

No. QWO is an injectable treatment option that is thought to target a primary structural cause of cellulite— the fibrous septae.1,2 The exact mechanism for the treatment of moderate to severe cellulite is unknown.

How do I know if QWO is right for me?

Your doctor will determine if you are an appropriate candidate for QWO.

Can QWO be used to treat cellulite in other areas besides the buttocks?

QWO is only approved for treatment of moderate to severe cellulite in the buttocks of adult women. Endo Aesthetics is continuing to investigate additional areas of treatment.

How many treatments will I need?

Each treatment visit may include up to two treatment areas. QWO injections will be given three weeks apart for a total of three treatment visits.

Are there side effects of QWO?

There are risks associated with this product. QWO may cause serious side effects including: allergic (hypersensitivity) reactions, including anaphylaxis, and injection site bruising.1 These are not all the side effects of QWO. Please see Important Safety Information on the next page for more details.

Where is QWO available?

QWO is now available throughout the United States at aesthetic healthcare practitioners’ offices.

Before And After Photos

Patient 1

  • Age 47
  • Fitzpatrick IV
  • BMI 8
  • Category Normal Weight
EA QW 05414 Before and After Photos R31

Patient 2

  • Age 52
  • Fitzpatrick II
  • BMI 6
  • Category Normal Weight
EA QW 05414 Before and After Photos R32

Patient 3

  • Age 21
  • Fitzpatrick III
  • BMI 22
  • Category Normal Weight
EA QW 05414 Before and After Photos R33

Indication And Important Safety Information

What Is QWO?

QWO is a prescription medicine used to treat moderate to severe cellulite in the buttocks of adult women.

Important Safety Information

Do not receive QWO if you: are allergic to collagenase or to any of the ingredients in QWO, or have an active infection at the treatment area.

QWO may cause serious side effects, including:

  • Allergic (hypersensitivity) reactions, including anaphylaxis. Call your healthcare provider right away if you have hives, trouble breathing, low blood pressure, swollen face, chest pain, dizziness or fainting after receiving QWO;
  • Injection site bruising

Before receiving QWO, tell your healthcare provider if you:

  • have a bleeding problem
  • are pregnant or may become pregnant, nursing or plan to nurse. You and your healthcare provider should decide if you will receive QWO or breastfeed.

Tell your healthcare provider about all the medicines you take, including prescription and over-the- counter medicines, vitamins and herbal supplements. Especially tell your healthcare provider if you take a medicine that prevents the clotting of your blood (antiplatelet or anticoagulant).

The most common side effects of QWO include: injection site bruising, pain, areas of hardness, itching, redness, discoloration, swelling and warmth in the treatment area.

These are not all the possible side effects of QWO. Call your healthcare provider for medical advice about side effects. You are encouraged to report side effects of prescription drugs to the FDA
at or 1-800-FDA-1088.

Click for Full Prescribing Information, including Patient Information for QWO.

For more information, please visit


  1. QWO [prescribing information]. Malvern, PA: Endo Aesthetics LLC.
  2.  Hexsel D, Mazzuco R. Cellulite. In: Tosti A, Hexsel D, eds. Update in Cosmetic Dermatology. Vol 1. 1st ed. Berlin/Heidelberg,

QWO® is a registered trademark and Endo Aesthetics™ is a trademark of Endo International plc or one of its affiliates.
© 2021 Endo Aesthetics LLC. All rights reserved. Malvern, PA 19355 EA-QW-05304/February 2021

Book an Appointment

* All indicated fields must be completed.

Please include non-medical questions and correspondence only.

Accessibility Toolbar

Scroll to Top